Dr. Regina Zambrano DiFiore

About Dr. Zambrano DiFiore

Dr. Regina Zambrano DiFiore, DO

Board-Certified Dermatologist | Medical, Pediatric & Cosmetic Dermatology

Dr. Regina Zambrano DiFiore is a board-certified dermatologist at the Skin Institute of New York (SINY®), providing comprehensive dermatologic care at the Massapequa, Long Island location. Born and raised on the South Shore of Long Island, Dr. Zambrano DiFiore is proud to serve the community she calls home, caring for patients of all ages with a compassionate, highly personalized approach.

She is trained in medical, pediatric, and cosmetic dermatology, with advanced experience treating all skin types. Patients appreciate her thorough evaluations, clear communication, and commitment to developing treatment plans that align with each individual’s needs and goals.

Schedule an Appointment with Dr. Zambrano DiFiore

Education & Training

Dr. Zambrano DiFiore’s academic excellence and leadership background reflect her dedication to high-quality, evidence-based dermatologic care:

• Bachelor of Science in Biology (Honors) – Stony Brook University
  Specialization: Developmental Genetics
• Doctor of Osteopathic Medicine (DO) – Nova Southeastern University, Fort Lauderdale, FL
• Master of Public Health (MPH) – Nova Southeastern University
• Internship & Dermatology Residency – St. John’s Episcopal Hospital
  Chief Resident, Final Year

Her dual medical and public health training allows Dr. Zambrano DiFiore to approach dermatology with a broad, patient-centered perspective that emphasizes both treatment and long-term skin health.

Clinical Expertise & Special Interests

Dr. Zambrano DiFiore provides comprehensive care for conditions affecting the skin, hair, and nails, including both common and complex dermatologic concerns. Her areas of focus include:

• Medical dermatology for acute and chronic skin conditions
• Pediatric dermatology
• Skin cancer screening and early detection
• Hair and scalp disorders
• Nail conditions
• Cosmetic dermatology, including:
• Neurotoxins (Botox® and similar treatments)
• Dermal fillers

With a thoughtful, minimalistic approach to aesthetics, she focuses on enhancing her patients’ natural beauty—creating treatment plans that are subtle, balanced, and tailored to individual goals. Her philosophy centers on helping patients look refreshed, confident, and like the best version of themselves.

Patient-Centered Philosophy

Dr. Zambrano DiFiore is deeply committed to building long-term relationships with her patients. She strives to create an approachable, supportive environment where patients feel heard, respected, and actively involved in their care.

She is passionate about patient education, empowering individuals to understand their conditions and treatment options so they can confidently participate in their dermatologic journey. Dr. Zambrano DiFiore remains actively engaged with the latest advancements in dermatology to ensure her patients receive safe, effective, and innovative care.

Patient Experience & Satisfaction

Patients consistently describe Dr. Zambrano DiFiore as attentive, knowledgeable, and genuinely caring. Many highlight her ability to listen closely, explain treatment options clearly, and follow up personally to ensure optimal outcomes.

Convenient Location in Long Island

Dr. Zambrano DiFiore sees patients at the SINY Dermatology Massapequa office, serving families and individuals throughout the South Shore of Long Island.

Massapequa, Long Island

83A Grand Ave, Massapequa, NY 11758

Phone: 800-778-3090

Hours:

• Mon, Thu & Fri: 9:00 AM – 5:00 PM
• Tue: 12:00 PM – 8:00 PM
• Wed: Closed
• Sat: By appointment
• Sun: Closed

Serving patients from: Massapequa, Massapequa Park, Seaford, Wantagh, Bellmore, Amityville, Farmingdale, and surrounding Long Island communities.

Schedule an Appointment at Massapequa

Accepted Insurance Plans

Dr. Zambrano DiFiore accepts many major insurance plans commonly used throughout Long Island and New York, including:

• Aetna
• Anthem Blue Cross Blue Shield / Empire Blue Cross Blue Shield
• Blue Cross Blue Shield
• Cigna & Cigna-HealthSpring
• UnitedHealthcare & Oxford
• EmblemHealth (GHI)
• Healthfirst (NY)
• Medicare
• Humana
• Fidelis Care (NY)
• AvMed
• 1199SEIU
• Multiplan PHCS

Additional plans may be accepted. Please contact SINY Dermatology to confirm coverage prior to your visit.

About SINY Dermatology (Skin Institute of New York)

The Skin Institute of New York (SINY®) is a leading dermatology group providing medical, surgical, and cosmetic dermatology services across New York. SINY Dermatology physicians combine academic excellence, advanced clinical training, and patient-focused care to deliver high-quality, individualized treatment for every patient.