Dr. Regina Zambrano DiFiore
Board-Certified Dermatologist located in Brooklyn, NY & West Village, New York, NY
About Dr. Zambrano DiFiore
Dr. Regina Zambrano DiFiore is a board-certified dermatologist at the Skin Institute of New York (SINY®), where she sees patients at the Massapequa, Long Island office. Born and raised on the south shore of Long Island, Dr. Zambrano is honored to return to her community and provide expert dermatologic care to patients of all ages. She is trained in medical, surgical, pediatric, and cosmetic dermatology, and has advanced experience treating all skin types with a compassionate, personalized approach.
Dr. Zambrano graduated with honors from Stony Brook University, where she earned her Bachelor of Science degree in Biology with a specialization in Developmental Genetics. She went on to complete both her Medical degree and Master of Public Health degree simultaneously at Nova Southeastern University in Fort Lauderdale, Florida. Following medical school, she completed her Internship and Dermatology Residency at St. John’s Episcopal Hospital, where she served as a Chief Resident in her final year.
In her practice, Dr. Zambrano provides comprehensive care for conditions of the skin, hair, and nails, ranging from common dermatologic concerns to more complex disorders. She is extensively trained in cosmetic dermatology, including the use of neurotoxins, fillers, and lasers. With a strong belief in enhancing her patients’ natural beauty, she takes a thoughtful, minimalistic approach to aesthetics—tailoring treatment plans and skincare regimens to each individual’s unique needs and goals. Her philosophy centers on helping patients look and feel like the very best version of themselves.
Dedicated to forming lasting relationships with her patients, Dr. Zambrano strives to create an approachable and supportive environment where every patient feels truly cared for. She is passionate about educating her patients and empowering them to take part in their treatment journey. Her commitment to dermatology extends beyond the clinic—she stays current with the latest advances in the field to bring safe, effective, and innovative care to her community.
Outside of medicine, Dr. Zambrano enjoys spending time with her husband, their two young children, and their beloved Goldendoodle. She feels privileged to be serving the community where she grew up, and looks forward to providing high-quality dermatologic care to the families of Long Island for years to come.

Dr. Regina Zambrano DiFiore is a board-certified dermatologist at the Skin Institute of New York (SINY®), where she sees patients at the Massapequa, Long Island office. Born and raised on the south shore of Long Island, Dr. Zambrano is honored to return to her community and provide expert dermatologic care to patients of all ages. She is trained in medical, surgical, pediatric, and cosmetic dermatology, and has advanced experience treating all skin types with a compassionate, personalized approach.
Dr. Zambrano graduated with honors from Stony Brook University, where she earned her Bachelor of Science degree in Biology with a specialization in Developmental Genetics. She went on to complete both her Medical degree and Master of Public Health degree simultaneously at Nova Southeastern University in Fort Lauderdale, Florida. Following medical school, she completed her Internship and Dermatology Residency at St. John’s Episcopal Hospital, where she served as a Chief Resident in her final year.
In her practice, Dr. Zambrano provides comprehensive care for conditions of the skin, hair, and nails, ranging from common dermatologic concerns to more complex disorders. She is extensively trained in cosmetic dermatology, including the use of neurotoxins, fillers, and lasers. With a strong belief in enhancing her patients’ natural beauty, she takes a thoughtful, minimalistic approach to aesthetics—tailoring treatment plans and skincare regimens to each individual’s unique needs and goals. Her philosophy centers on helping patients look and feel like the very best version of themselves.
Dedicated to forming lasting relationships with her patients, Dr. Zambrano strives to create an approachable and supportive environment where every patient feels truly cared for. She is passionate about educating her patients and empowering them to take part in their treatment journey. Her commitment to dermatology extends beyond the clinic—she stays current with the latest advances in the field to bring safe, effective, and innovative care to her community.
Outside of medicine, Dr. Zambrano enjoys spending time with her husband, their two young children, and their beloved Goldendoodle. She feels privileged to be serving the community where she grew up, and looks forward to providing high-quality dermatologic care to the families of Long Island for years to come.